A Simulation Analysis of an Influenza Vaccine Production Plant in Areas of High Humanitarian Flow. A Preliminary Study for the Region of Norte de Santander (Colombia)

The production of vaccines biological origin presents a tremendous challenge for researchers. In this context, animal cell cultures are an excellent alternative the isolation and biologicals against several viruses, since they have affinity with viruses great capacity their replicability. Different variables been studied to know system’s ideal parameters, allowing it obtain profitable competitive products. Consequently, work focuses its efforts on evaluating producing anti-influenza from MDCK cells using SuperPro Designer v8.0 software. process uses DMEN culture medium supplemented nutrients as raw material development; were obtained potential scale-up final working volume 500 L, four days residence time, inoculum 10%, continuous mode up total 7400 h/Yr work. scheme has necessary equipment vaccine’s production, infection, manufacture yields 416,698 units/h. addition, was estimated be economically viable produce recombinant prices 0.31 USD/unit.